THE KZH LAB

School of Biomedical Sciences, LKS Faculty of Medicine, HKU

Publications

1.Keda Zhou, Magdalena Gebala, Dustin Woods, Kousik Sundararajan, Garrett Edwards, Dan Krzizike, Jeff Wereszczynski, Aaron F. Straight, and Karolin Luger. (2022), CENP-N promotes the compaction of centromeric chromatin.NATURE STRUCTURE AND MOLECULAR BIOLOGY.29 (4), 403-413

 

2. Yang Liu *,Keda Zhou *, Naifu Zhang, Hui Wei, Yong Zi Tan, Zhening Zhang, Bridget Carragher, Clinton S Potter, Sheena D'Arcy, Karolin Luger, (2020), FACT caught in the act of manipulating the nucleosome.NATURE, 577, 426-431.*co-first author, equal contribution.

 

3.Keda Zhou, Yang Liu, Karolin Luger, (2020), Histone chaperone FACT FAcilitates Chromatin Transcription: mechanistic and structural insights.CURRENT OPINION IN STRUCTURAL BIOLOGY, 65, 26-32.

 

4.Keda Zhou *, Guillaume Gaullier* and Karolin Luger, (2019), Nucleosome structure and dynamics are coming of age.NATURE STRUCTURAL AND MOLECULAR BIOLOGY, 26, 3-13.*co-first author, equal contribution.

 

5. Satyakrishna Pentakota *,Keda Zhou *, Charlotte Smith, Stefano Maffini, Arsen Petrovic, Garry P. Morgan, John R. Weir, Ingrid R. Vetter, Andrea Musacchio & Karolin Luger, 2017, Decoding the centromeric nucleosome through CENP-N. eLife. 6: e33442.* co-first author, equal contribution.

 

6. Shengya Cao *,Keda Zhou *, Zhening Zhang, Karolin Luger, Aaron F. Straight, (2017), Constitutive centromere-associated network contacts confer differential stability on CENP-A nucleosomes in vitro and in the cellMOLECULAR BIOLOGY OF THE CELL, E17-10_0596.* co-first author, equal contribution.

 

7. Yang Liu, Hugo Bisio, Chelsea Marie Toner, Sandra Jeudy, Nadege Philippe, Keda Zhou, Samuel Bowerman, Alison White, Garrett Edwards, Chantal Abergel and Karolin Luger. (2021), Virus-encoded histone doublets are essential and form nucleosome-like structures.CELL, 184(16):4237-4250.e19.

 

8. Yelagandula, R., Hume Stroud, Sarah Holec, Keda Zhou, Suhua Feng, Xuehua Zhong, Uma M. Muthurajan, Xin Nie, Tomokazu Kawashima, Martin Groth, Karolin Luger, Steven E. Jacobsen, and Frederic Berger, (2014) The histone variant H2A.W defines heterochromatin and promotes chromatin condensation inArabidopsis.CELL, 158, 98-109.

 

9. Uma Muthurajan, Francesca Mattiroli, Serge Bergeron, Keda Zhou, Yajie Gu, Srinivas Chakravarthy, Pamela Dyer, Thomas Irving, and Karolin Luger, (2016), In vitro Chromatin Assembly - Strategies and Quality Control. METHODS ENZYMOL. 573: 3-41.

 

10. Jonathan W Markert, Keda Zhou, Karolin Luger. (2021). Structure and function of the chromatin remodeler SMARCAD1 with its nucleosome substrate.SCIENCE ADVANCE.7 (42), eabk2380.

11. Hengyou Weng, Feng Huang, Zhaojin Yu, Zhenhua Chen, Emily Prince, Yalin Kang, Keren Zhou, Wei Li, Jiacheng Hu, Chen Fu, Tursunjan Aziz, Hongzhi Li, Jingwen Li, Ying Yang, Li Han, Subo Zhang, Yuelong Ma, Mingli Sun, Huizhe Wu, Zheng Zhang, Mark Wunderlich, Sean Robinson, Daniel Braas, Johanna Ten Hoeve, Bin Zhang, Guido Marcucci, James C Mulloy, Keda Zhou, Hong-Fang Tao, Xiaolan Deng, David Horne, Minjie Wei, Huilin Huang, Jianjun Chen. (2022) The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia. Cancer cell.